Rationale engineering generates a compact new tool for gene therapy
Researchers redesign a compact RNA-guided enzyme from bacteria, making it an efficient editor of human DNA.
Broad Institute
With AI, researchers predict the location of virtually any protein within a human cell
Trained with a joint understanding of protein and cell behavior, the model could help with diagnosing disease and developing new drugs.
An ancient RNA-guided system could simplify delivery of gene editing therapies
The programmable proteins are compact, modular, and can be directed to modify DNA in human cells.
A causal theory for studying the cause-and-effect relationships of genes
By sidestepping the need for costly interventions, a new method could potentially reveal gene regulatory programs, paving the way for targeted treatments.
A fast and flexible approach to help doctors annotate medical scans
“ScribblePrompt” is an interactive AI framework that can efficiently highlight anatomical structures across different medical scans, assisting medical workers to delineate regions of interest and abnormalities.
AI model identifies certain breast tumor stages likely to progress to invasive cancer
The model could help clinicians assess breast cancer stage and ultimately help in reducing overtreatment.
School of Engineering welcomes new faculty
Fifteen new faculty members join six of the school’s academic departments.
New AI method captures uncertainty in medical images
By providing plausible label maps for one medical image, the Tyche machine-learning model could help clinicians and researchers capture crucial information.
Using AI, MIT researchers identify a new class of antibiotic candidates
These compounds can kill methicillin-resistant Staphylococcus aureus (MRSA), a bacterium that causes deadly infections.
Search algorithm reveals nearly 200 new kinds of CRISPR systems
By analyzing bacterial data, researchers have discovered thousands of rare new CRISPR systems that have a range of functions and could enable gene editing, diagnostics, and more.